Ketogenic diet and autoimmune diseases? What is the relation?

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Ketogenic diet and autoimmune diseases? What is the relation?

Ketogenic diet and autoimmune diseases? What is the relation?

Making changes in your diet can drastically improve your symptoms of autoimmune disease or even send your illness to remission. But what diet is better if you want to get an autoimmune condition under control? Relation between the ketogenic diet and autoimmune disease is still under debate. But be the diet you choose; make sure it fights instead of feeding inflammation.

As you might have heard, autoimmune disease is rooted in chronic inflammation. The long-term inflammation caused by various factors confuses its immune system and makes it attack the organs and parts of the body that it does not want it to attack. But the diet is one of the best ways to fight against chronic inflammation contributing to your illness.

Ketogenic diet and autoimmune diseases

The Keto diet and Inflammation diseases in Intestine 

According to the National Institutes of Health (N.I.H.), more than 80 chronic autoimmune diseases affect more than 23.4 million Americans. Some who may know include rheumatoid arthritis, Hashimoto’s thyroiditis, lupus, celiac, multiple sclerosis, and tomb disease, to name a few.

Researchers at the University of California (U.S.A.), San Francisco (U.S.A.), have just confirmed that there is a relation between the ketogenic diet and autoimmune disease. Keto’s diet changes the intestine, reduces inflammation, and could help people suffering from autoimmune disorders.

Consumption of Super-low Carbs

If you are unaware of the Keto diet, here are the cliff notes it is a deficient diet in carbohydrates and high fat that triggers significant metabolic changes in your body. By maintaining the consumption of super-low carbons, the Keto diet requires your body to change the carbohydrates for fuel to use fat molecules called fuel ketones.

This previous study included 17 overweight or obese roundabout men. The researchers asked these men to spend two months as hospitalized patients in a metabolic neighborhood to keep track of their diets and exercise habits.

The researchers asked half of these men to eat a standard diet during the first four weeks, and This diet consisted of 35 percent fat, 15 percent protein, and 50 percent carbohydrates; the other half ate a ketogenic diet composed of 5 percent carbohydrates, 80 percent fat and 15 percent protein. In the second four weeks, the two groups changed diets.

The researchers took a look at the stool samples to analyze the difference in the microbiomes of these men as they changed between the standard diets and Keto diets. And here is what they found.

The Keto diet made some dramatic changes to their microbiomes. There were changes in at least 19 different bacteria, including those that fell into these categories: Actinobacteria, Bacteroides, and Firmicutes. The diet also made significant changes in common probiotic bifidobacteria intestinal levels. These levels fell a lot.

What did these changes mean for the long-term health of these men?

To explore that question, the researchers transplanted the microbiomes components of humans after Keto’s diet in mice. They discovered that the microbial changes caused by the keto diet reduced the number of Th17 immune cells in these mice. Th17 immune cells are a kind of T cell that assists with combatting the disease. 

Unfortunately, it is a fact that these immune cells promote inflammation in autoimmune diseases. Then, less of them could mean less inflammation and perhaps even less flashing of autoimmune disease.

The researchers made a little more exploration on how Keto’s diet influenced the microbiomes of mice. They changed their diets between low-fat ketogenic diets, high fat, and low carbohydrates, And discovered another exciting information about it. They changed their diets between low-fat ketogenic diets, high fat, and low carbohydrates. And found another exciting announcement for those who consider covering a new diet. 

High-fat and Ketogenic Diet

High-fat and ketogenic diets have an opposite impact on the intestinal microbiome. That means that the low carbohydrate part of Keto is critical. Eating a lot of fat without cutting the carbohydrates enough will not make your microbiome any favorite.

Consider these autoimmune diets before going to Keto.

Should I go to Keto so that your autoimmune disease is under control? It seems that it has potential. But at this point, there are some other diets with more research to support your benefits from autoimmune disease. That diet is the autoimmune protocol diet (A.I.P.). This diet is a change from the Paleo diet, which is also low in carbohydrates but not so common in carbohydrates like the Keto diet.

Keto diet and Inflammation diseases

A.I.P Diet 

The A.I.P. diet begins with an initial elimination phase where it stops eating grains, legumes, nocturnal, dairy, eggs, coffee, alcohol, nuts and seeds, refined sugars, oils, and food additives. This elimination is because it is a fact that these foods cause intestinal inflammation, imbalances of microbiomes, and cause food intolerances. 

While eliminating these foods, it also focuses on eating healthier foods, such as fresh nutrients, dense nutrients, bone broth, and fermented foods (a significant source of Lactobacillus, which increases blood levels from inflammation of vitamin D). Eventually, it enters a maintenance phase where you start adding food to your diet to see which can be bearable and the activation symptoms.

Wahl’s Protocol

Wahl’s protocol is another excellent option for people with autoimmune diseases. It’s a variation on the paleo diet as well. Still, this one was by an expert, a clinical professor of medicine at the University of Iowa, who used it to send her secondary progressive multiple sclerosis into remission successfully.

Wahl’s protocol has successfully treated individuals with corpulence, diabetes, exhaustion, constant torment, lupus, rheumatoid joint pain, provocative entrail sickness, post-horrible pressure issue, and horrendous cerebrum injury. In this way, it merits investigating, assuming you experience the ill effects of these or other immune system sicknesses.


In conclusion, ketogenic diets appear to be a new promising therapy, although it is early to know its effectiveness and scope. Taking into account that diet is the primary modulator of the intestinal microbiota. 

The Keto microbiota could be a critical factor in the chemotherapeutic effects since the microbiome operates a strong network between the different organs. However, more clinical and preclinical studies are required to define the ideal K.D.S. exposure time, or that fail, “Keto microbiota profile,” to achieve a correct functioning in different pathologies.

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